의과대학 - 의과대학

  • 부교수 약제과학(약물전달/세포치료제)
  • 정지헌
    Lab 약물전달 및 세포치료 실험실

관심분야

Targeted Drug Delivery System, Cell Therapy

학력

  • 충남대학교 약학대학 약학사
  • 서울대학교 약학대학 약학박사

학술지 논문

  • (2023)  Magnetic resonance imaging of pancreatic islets using tissue–adhesive particles containing iron oxide nanoparticles.  JOURNAL OF CONTROLLED RELEASE.  364, 
  • (2023)  Liposomal co-delivery of toll-like receptors 3 and 7 agonists induce a hot triple-negative breast cancer immune environment.  JOURNAL OF CONTROLLED RELEASE.  361, 
  • (2023)  Integrative Evaluation of the Clinical Significance Underlying Protein Arginine Methyltransferases in Hepatocellular Carcinoma.  CANCERS.  15,  16
  • (2023)  Nanoengineered mesenchymal stem cell therapy for pulmonary fibrosis in young and aged mice.  SCIENCE ADVANCES.  9,  29
  • (2023)  Modulation of NLRP3 inflammasomes activation contributes to improved survival and function Modulation of NLRP3 inflammasomes activation contributes to improved survival and function of mesenchymal stromal cell spheroids.  MOLECULAR THERAPY.  31,  3
  • (2022)  T-cell engaging poly(lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing cancer.  BIOMATERIALS.  291,  -
  • (2022)  Prolongation of graft survival via layer-by-layer assembly of collagen and immunosuppressive particles on pancreatic islets.  BIOMATERIALS.  290,  -
  • (2022)  Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation.  SCIENCE ADVANCES.  8,  34
  • (2022)  Reactive oxygen species-responsive dual-targeted nanosystempromoted immunogenic cell death against breast cancer.  BIOENGINEERING & TRANSLATIONAL MEDICINE. 
  • (2021)  Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction.  AUTOPHAGY.  17,  10
  • (2021)  Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration.  BIOMATERIALS.  271,  1
  • (2021)  Surface-Triggered In Situ Gelation for Tunable Conformal Hydrogel Coating of Therapeutic Cells and Biomedical Devices.  ADVANCED FUNCTIONAL MATERIALS.  31,  21
  • (2019)  Inflammation-triggered local drug release ameliorates colitis by inhibiting dendritic cell migration and Th1/Th17 differentiation.  JOURNAL OF CONTROLLED RELEASE.  316, 
  • (2019)  Engineering "cell-particle hybrids" of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation.  BIOMATERIALS.  221, 
  • (2019)  Immunoisolation of pancreatic islets via thin-layer surface modification.  JOURNAL OF CONTROLLED RELEASE.  305, 
  • (2019)  Mesenchymal Stem Cell Capping on ECM-Anchored Caspase Inhibitor-Loaded PLGA Microspheres for Intraperitoneal Injection in DSS-Induced Murine Colitis.  SMALL.  15,  23